The group is led by Dr Yalda Jamshidi, and comprises a diverse group of scientists at all levels who are passionate about genetics.
Yalda is Reader in Genomic Medicine at St George's University of London where she co-directs the Genetics Research Centre. She trained at University College London and completed postdoctoral fellowships at the Institute of Child Health and Kings College London before taking an academic position at St.George’s in 2006.
Dr Jamshidi’s research interests focus on understanding the genetic and molecular mechanisms of electrocardiographic structure and function at the population level. She also has a key interest in the use of the latest genetic technologies to uncover the underlying genetic causes of rare inherited conditions. Her group is applying the discoveries, and novel technologies, to identify genes and pathways which can lead to increased susceptibility to rare cardiac arrhythmias, cardiomyopathies, and drug-induced cardiotoxicity. Her aim is to translate genetic discoveries into an improved understanding of human physiology through clinically-focused research, and define the role of genetics in disease diagnosis and in predicting patients’ risk of disease.
OUTREACH AND EDUCATION
Dr Jamshidi has a Postgraduate Certificate in Healthcare and Biomedical Education and has taught molecular biology and genetics to medical, BSc and PhD/MRes students. She initiated and runs the Cloning, Stem Cell Research and Regenerative Medicine module offered to medical students who choose to undertake an Intercalated BSc, and to third year Biomedical Science BSc students. She also acts as module co-ordinator for a Cardiovascular Genetics module on the MSc in Genomic Medicine offered at St George's.
She is personal tutor to both Medical students and Biomedical Science BSc students, and is currently an external examiner for the Genomic Medicine MSc at Exeter University.
She is an elected Fellow of the Royal Society of Biology (as of April 2016), a local representative for the Genetics Society. She is a member of the editorial board for the Physiological Genomics Journal and the Journal Genes.
She is keen to share her excitement about our research with the public through seminars at local schools, interactions on social media, and talking to patient advocacy groups to see what the patients themselves want from our research. She also works with the Science Media Centre, an independent press office helping to ensure that the public have access to the best scientific evidence and expertise through the news media when science hits the headlines.
Visit our outreach page to learn more about our work outside of the lab!
POST-DOCS and GRADUATE STUDENTS
Reza recently completed a PhD entitled "Defining the genetic causes of neurodevelopmental disorders in the Amish". His project defined a wide range of known genetic causes of NDDs, provided novel biological insight into the roles of key proteins in neuronal structure and brain function, and identified new genes and pathways involved in disease. He is now working on a broad range of disorders within consanguineous families, trying to identify their underlying genetic cause. Click here to see publications.
Jay is carrying out a PhD with Yalda Jamshidi and Daniel Osborn. She is looking at the role of a novel transcriptional regulator of muscle using the zebrafish model.
Oliver Hines is working with Yalda Jamshidi and Karla Diaz-Ordaz (LSHTM) on an MRC-LID PhD project to look at machine learning and improving statistical methodology to determine causal genetic variants for heart rhythm. Oliver did his undergraduate degree at Imperial in the Department of Physics and has recently completed an MSc in Statistics in the Department of Mathematics at Imperial.
Prof Harold Snieder, Dr Ilja Nolte - University of Groningen, The Netherlands
Prof Tim D Spector, TwinsUK, Department of Twin Research and Epidemiology, Kings College London, UK
Prof Nona Sotoodehnia, University of Washington, Seattle, US.
In vivo models:
Dr Dan Osborn, SGUL Genetics Centre
Dr Chris Carroll, SGUL Genetics Centre
Dr Ehsan Karimiani, Honorary Lecturer, St George's Uni. London.
Dr Chiara Manzini, George Washington University, Washington DC, US.
Dr Dongling Zheng - Post Doc
MRes Biomedical Science Students:
William Stockdale Cardiovascular Genetics (Distinction) 2014/15
Jaipreet Bharj Cardiovascular Genetics (Merit) 2013/14 Evmorfia Petropoulou Cardiovascular Genetics (Distinction) 2012/13 Merve Uysaloglu Cardiovascular Genetics (Distinction) 2012/13
Thulasi Nithiyananthan Cardiovascular Genetics (Distinction) 2007/08
undergraduate Biomedical Science/medical Students:
Siavash Tohidi, Yusof Ali (2015/2016)
Hamza Naeem, Ali Sohail, Chantal Roberts, Huda Khalif (2014/2015)
Sokol Shala, Joao Pequeno Vieira (2013/2014)
Nardos Abraham (2016/2017)
Heather Jeffery (awarded Genetics Society summer studentship, 2016)